Extended ANA profile -44 Parameters – (Jo-1/ PL-7/ PL-12/ EJ/ OJ/ KS/ YARS/ ZoA/ ZoB/ HMGCR/ SAE-1/ SAE-2/ SRP54/ Mi-2/ TIF1γ/ MDA5/ NXP2/ PMScl 100/ PMScl 75/ M2/ DFS70/ Scl70/ CENP A/ CENP B/ POLR3A/ NOR90/ Th,To/ PDGFR-β/ Fibrillarin/ Ro52/ Ro60/ La/ PCNA/ P0/ SmB/ SmD/ Nucleolin/ Nucleosome/ Histone/ RNP A/ RNP 68/ RNP C /Ku/ dsDNA)

Description

**Extended ANA Profile – 44 Parameters**

The Extended ANA Profile – 44 Parameters is a comprehensive diagnostic test designed to evaluate the presence of specific autoantibodies associated with autoimmune diseases. This test analyzes 44 critical markers, including Jo-1, PL-7, PL-12, EJ, OJ, KS, YARS, ZoA, ZoB, HMGCR, SAE-1, SAE-2, SRP54, Mi-2, TIF1γ, MDA5, NXP2, PMScl 100, PMScl 75, M2, DFS70, Scl70, CENP A, CENP B, POLR3A, NOR90, Th, To, PDGFR-β, Fibrillarin, Ro52, Ro60, La, PCNA, P0, SmB, SmD, Nucleolin, Nucleosome, Histone, RNP A, RNP 68, RNP C, Ku, and dsDNA. By providing a detailed analysis of these markers, this test aids in the diagnosis, monitoring, and management of autoimmune conditions such as systemic lupus erythematosus (SLE), scleroderma, polymyositis, dermatomyositis, and other connective tissue disorders.

**Why You Need This Test**
The Extended ANA Profile is essential for individuals experiencing symptoms or conditions that may indicate an autoimmune disorder. Autoimmune diseases occur when the immune system mistakenly attacks the body’s own tissues, leading to inflammation and damage. This test provides a detailed assessment of autoantibodies, which are critical in diagnosing and differentiating between various autoimmune conditions. Early detection through this test can help initiate timely treatment, prevent disease progression, and improve quality of life.

**Symptoms That Indicate This Test**
You may need the Extended ANA Profile if you experience any of the following symptoms:
– Persistent fatigue or weakness
– Unexplained joint pain or swelling
– Skin rashes, particularly on the face or hands
– Muscle pain or weakness
– Difficulty swallowing or breathing
– Sensitivity to sunlight
– Thickened or hardened skin
– Numbness or tingling in extremities
– Chronic dry eyes or mouth
– Unexplained fever or weight loss

These symptoms are often associated with autoimmune diseases such as lupus, scleroderma, Sjögren’s syndrome, or myositis, making this test a critical diagnostic tool.

**Natural Production**
Autoantibodies are proteins produced by the immune system that mistakenly target the body’s own tissues. While the immune system typically generates antibodies to fight infections, certain genetic, environmental, or hormonal factors can trigger the production of autoantibodies. These factors may include infections, stress, exposure to toxins, or a family history of autoimmune diseases. The Extended ANA Profile evaluates these autoantibodies to identify potential autoimmune activity in the body.

**What Happens If Untreated**
If autoimmune conditions are left undiagnosed or untreated, they can lead to severe complications, including organ damage, chronic pain, and disability. For example, untreated lupus can result in kidney failure, while scleroderma may cause life-threatening lung or heart complications. Early detection through the Extended ANA Profile allows for timely intervention, reducing the risk of long-term damage and improving overall health outcomes.

**How to Prepare for the Test**
To ensure accurate results, follow these preparation guidelines:
– No fasting is required for this test.
– Inform your healthcare provider about any medications or supplements you are taking, as certain drugs may influence test results.
– Avoid strenuous physical activity or stress before the test, as these factors can affect autoantibody levels.

**Test Overview**
– **Sample Type**: Serum
– **Methodology**: Micro Array Blot
– **Turnaround Time (TAT)**: 3 Days

This test requires a blood sample, which is analyzed using advanced microarray blot technology to detect and quantify autoantibodies. Results are typically available within three days, providing timely insights into your health.

**Call to Action**
Take control of your health today with the Extended ANA Profile – 44 Parameters. Whether you’re experiencing symptoms or seeking a comprehensive evaluation for autoimmune conditions, this test offers the detailed insights you need. Book your lab test online now and get accurate results from a trusted diagnostic provider. Don’t wait—early detection is key to managing your health effectively.

**Category**: Autoimmune Disease Testing