Celiac Profile – Basic

Description

**Celiac Disease Antibody Panel – Gliadin & Transglutaminase IgA & IgG**

**Turnaround Time:** 7 Days
**Parameters Tested:**
– Gliadin Antibody IgA & IgG
– Transglutaminase IgA & IgG

### **Overview**
The **Celiac Disease Antibody Panel** is a specialized blood test designed to detect immune system responses associated with celiac disease and gluten sensitivity. This test measures **Gliadin Antibodies (IgA & IgG)** and **Transglutaminase Antibodies (IgA & IgG)** to assess gluten intolerance and autoimmune reactions. It is ideal for individuals experiencing digestive issues, unexplained nutrient deficiencies, or autoimmune-related symptoms.

### **Why You Need This Test**
Celiac disease is an autoimmune disorder where gluten consumption triggers an immune response, damaging the small intestine. This test helps:
– **Diagnose celiac disease** by detecting antibodies linked to gluten intolerance.
– **Monitor gluten-free diet effectiveness** in individuals with diagnosed celiac disease.
– **Identify non-celiac gluten sensitivity** in individuals with persistent symptoms.
– **Prevent long-term complications** such as malabsorption, osteoporosis, and neurological disorders.

### **Symptoms That Indicate This Test**
Consider this test if you experience:
– Chronic diarrhea or constipation
– Bloating, gas, or abdominal pain
– Unexplained weight loss
– Fatigue and brain fog
– Skin rashes (dermatitis herpetiformis)
– Joint pain or muscle weakness
– Iron deficiency anemia
– Family history of celiac disease or autoimmune disorders

### **Natural Production & Regulation**
The immune system naturally produces **IgA and IgG antibodies** to protect against harmful substances. However, in individuals with celiac disease, the body mistakenly targets gluten proteins, leading to inflammation and intestinal damage. **Tissue transglutaminase (tTG)** is an enzyme involved in protein modification, and its antibodies (tTG-IgA & tTG-IgG) are key markers of celiac disease.

### **What Happens If Untreated?**
Ignoring gluten intolerance or celiac disease can lead to:
– Chronic malabsorption and nutrient deficiencies
– Increased risk of osteoporosis and fractures
– Infertility and pregnancy complications
– Neurological issues like migraines and neuropathy
– Higher risk of autoimmune diseases (e.g., type 1 diabetes, thyroid disorders)

### **How to Prepare for the Test**
– **Continue consuming gluten** before testing for accurate results. Avoiding gluten may lead to false negatives.
– No fasting required.
– Inform your doctor about any medications or supplements that may affect results.

### **Test Details**
– **Sample Type:** Blood
– **Test Method:** Enzyme-linked immunosorbent assay (ELISA)
– **Turnaround Time:** 7 Days
– **Accuracy & Reliability:** High sensitivity and specificity for celiac disease detection

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Order your **Celiac Disease Antibody Panel** today for a comprehensive gluten sensitivity assessment and take control of your digestive health!