Immunohistochemistry ER, PR, HER2/neu Testing – Paraffin Embedded Block/Charged Slides | 7-Day TAT | Histo Analysis

Description

### Immunohistochemistry ER, PR, HER2/neu Testing – Paraffin Embedded Block/Charged Slides | 7-Day TAT | Histo Analysis

#### Why You Need This Test
The Immunohistochemistry ER, PR, HER2/neu Testing is a critical diagnostic tool for evaluating the expression of estrogen receptor (ER), progesterone receptor (PR), and HER2/neu protein in paraffin-embedded tissue samples. These biomarkers are essential in diagnosing and managing breast cancer, as they provide detailed insights into tumor biology. This test helps oncologists determine the hormone receptor status and HER2/neu overexpression, which are pivotal in guiding personalized treatment strategies. By identifying these molecular markers, clinicians can recommend targeted therapies, such as hormone therapy or HER2-targeted treatments, improving patient outcomes and reducing unnecessary side effects.

#### Symptoms That Indicate This Test
This test is recommended for individuals experiencing symptoms or conditions that may indicate breast cancer or related abnormalities. These include:
– A palpable lump or thickening in the breast or underarm area.
– Changes in breast size, shape, or appearance.
– Persistent breast pain or tenderness.
– Nipple discharge, especially if bloody or clear.
– Skin changes on the breast, such as dimpling, redness, or scaling.
– A family history of breast cancer or genetic predisposition.
– Abnormal findings on mammograms or other imaging studies.

#### Natural Production
Estrogen and progesterone receptors are naturally present in certain cells and tissues, including breast tissue. These receptors bind to hormones like estrogen and progesterone, which regulate cell growth and function. HER2/neu is a protein involved in cell growth and repair, and its overexpression can lead to uncontrolled cell proliferation. Factors such as genetic mutations, hormonal imbalances, or environmental influences can alter the levels of these markers, potentially leading to the development of breast cancer. This test evaluates these markers to provide a comprehensive molecular profile of the tumor.

#### What Happens If Untreated
Ignoring abnormal levels of ER, PR, or HER2/neu can have serious consequences. Untreated hormone receptor-positive breast cancer may continue to grow and spread, reducing the chances of successful treatment. HER2-positive breast cancer, in particular, is known for its aggressive nature and rapid progression. Delayed diagnosis or treatment can lead to metastasis, where cancer spreads to other parts of the body, significantly impacting survival rates. Early detection through this test allows for timely intervention, improving prognosis and quality of life.

#### How to Prepare for the Test
Preparation for this test is straightforward. Patients should ensure that their paraffin-embedded tissue samples or charged slides are properly prepared and submitted to the laboratory. No additional fasting or medication adjustments are typically required. However, it is essential to consult with your healthcare provider for specific instructions based on your medical history and condition.

#### Test Overview
This test utilizes advanced immunohistochemical methodology to analyze paraffin-embedded tissue samples or charged slides. It evaluates the expression of ER, PR, and HER2/neu markers with high precision, ensuring reliable and accurate results. The test is designed to integrate seamlessly into standard histopathology workflows, requiring no specialized equipment. With a rapid 7-day turnaround time (TAT), it provides timely results, enabling clinicians to make informed decisions without delay.

#### Call to Action
Take control of your health today with the Immunohistochemistry ER, PR, HER2/neu Testing – Paraffin Embedded Block/Charged Slides | 7-Day TAT | Histo Analysis. Whether you are a patient seeking clarity or a clinician aiming for precision, this test is your trusted partner in breast cancer diagnosis and treatment planning. Don’t wait—book your lab test online now and ensure you have the critical information needed to make the best decisions for your health.

#### Additional Specifications
– **Sample Type:** Paraffin-embedded tissue block or charged slides.
– **Testing Methodology:** Immunohistochemistry (IHC).
– **Turnaround Time:** 7 days from sample receipt.
– **Purpose:** Evaluation of ER, PR, and HER2/neu expression for breast cancer diagnosis and treatment planning.

#### Histo Category
This test is categorized under Histo Analysis for easy navigation and accessibility.